Structural determinants of Smad function in TGF-β signaling
نویسندگان
چکیده
منابع مشابه
LAT-derived microRNAs in HSV-1 target SMAD3 and SMAD4 in TGF-β/Smad signaling pathway
Background: During its latent infection, HSV-1 produces only a miRNA precursor called LAT, which encodes six distinct miRNAs. Recent studies have suggested that some of these miRNAs could target cellular mRNAs. One of the key cell signaling pathways that can be affected by HSV-1 is the TGF-β/Smad pathway. Herein, we investigated the potential role of the LAT as well as three LAT-derived miRNAs ...
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ژورنال
عنوان ژورنال: Trends in Biochemical Sciences
سال: 2015
ISSN: 0968-0004
DOI: 10.1016/j.tibs.2015.03.012